Frequent scanning using flash glucose monitoring contributes to better glycemic control in children and adolescents with type 1 diabetes.

Aims /Introduction We examined the impact of scanning frequency with flash glucose monitoring (FGM) on glycemic control in children and adolescents with type 1 diabetes. Materials and methods The study included 85 patients, aged 14.0±0.5 years, with type 1 diabetes. The median time in the target glucose range (TIR) and glycosylated hemoglobin (HbA1c) values were 50.0±1.4% and 7.5±0.1%, respectively. Results The median scanning frequency using FGM was 12.0±0.4 times/ day. Scanning frequency showed a significant positive correlation with TIR and an inverse correlation with HbA1c. Scanning frequency was identified to be the determinant of TIR and HbA1c by using multivariate analysis. The subjects whose scanning frequency was below 12 times/ day were categorized as the low-frequency group (n=40), and those who performed the scanning above12 times/ day were categorized as the high-frequency group (n=45). Patients in the high-frequency group were more likely to be treated with insulin pumps compared to those in the low-frequency group; however, this difference was not significant (21.3 vs. 5.3%, P=0.073). The high-frequency group showed significantly greater TIR than the low-frequency group (57±1.6 vs. 42±1.7%, P=0.002). Moreover, the high-frequency group showed significantly lower HbA1c levels than the low-frequency group (6.8±0.1 vs. 8.0±0.1%, P Conclusions These findings demonstrated that patients with a higher scanning frequency had better glycemic control, with greater TIRs and lower HbA1c levels, compared to those with a lower scanning frequency. Scanning frequency of over 12 times/ day might contribute to better glycemic outcomes in real-world practice in children with type 1 diabetes. (250 words).