Chart validation of inpatient ICD‐9‐CM administrative diagnosis codes for acute myocardial infarction (AMI) among intravenous immune globulin (IGIV) users in the Sentinel Distributed Database

Background: The Sentinel Distributed Database (SDD) is a large database of patient-level administrative healthcare records, primarily derived from insurance claims and electronic health records, and is sponsored by the U.S. Food and Drug Administration for medical product safety evaluations. Acute myocardial infarction (AMI) is a common study endpoint for drug safety studies that rely on health records from the SDD and other administrative databases.