Analysis of risk factors for diabetic ketoacidosis

Objective:To investigate the risk factors of diabetic ketoacidosis.Method:Retrospectively analyzed the clinical data of 62 cases of diabetic ketoacidosis in the emergency department,and 72 cases of diabetic patient without ketoacidosis as the control group.Sex,age,infection history,improper diet,inappropriate treatment,hepatorenal dysfunction,course of diabetes and diabetes instruction were measured retrospectively.All the data was analyzed by spss 13.0 including chi-square test for counts material and independent sample T-test for measurement material.To exclude confounding factors,multivariat logistic regression analysis was performed.Result:Chi-square tests and independent sample T-tests showed that sex(P0.01),infection history(P0.01),inappropriate treatment(P0.05),course of diabetes(P0.05),diabetes instruction(P0.05) were influencing factors of diabetic ketoacidosis.However,multivariat logistic regression analysis revealed that infection history(P0.01;OR=4.192) and inappropriate treatment(P0.01;OR=3.719) were the independent risk factors for ketoacidosis in patients with diabetes,and sex(P0.01;OR=0.299),diabetes instruction(P0.05;OR=0.457) were independent protection factors.Conclusion:Infection history and inappropriate treatment are the independent risk factors for diabetic ketoacidosis,and there will be a significant decrease in the incidence rate of diabetic ketoacidosis with increasing age and getting rich of diabetes instruction.