Effect of Non-Surgical Periodontal Intervention in ChronicKidney Disease Patients: A Pilot Study

Background: Periodontal disease has been highlighted as an important potential risk factor for non-communicable diseases such as chronic kidney disease (CKD), diabetes mellitus, cardiovascular diseases, and pulmonary diseases. Studies have reported that patients suffering from end-stage renal failure (ESRF) and those receiving dialysis are more prone to compromised periodontal health status. Dialysis patients may form calculus more rapidly than healthy individuals possibly due to high salivary urea and phosphate levels. Studies prove that non-surgical periodontal therapy s??n?????ntl? improves the periodontal status and also reduces ?n?l?mm?tor? mediators which ultimately improve the glomerular ??ltr?t?on rate. Method: This was designed as a pilot study and was performed between 2018 and 2019. The inclusion criteria were CKD patients of age 18 and above. Data from medical records were collected, clinical oral examination was performed by recording periodontal pocket depth (PPD) p value: 0.001, clinical attachment loss (CAL) p value:0.000 ,bleeding on probing(BOP) p value:0.012, serum creatinine p value:0.035 , e-GFR p value:0.009. Non-surgical periodontal therapy was given to CKD patients at baseline and clinical periodontal data were statistically analysed. Result: Non-surgical periodontal therapy given to study group has resulted into s??n?????nt improvement in all the measured periodontal clinical parameters. Conclusion: this study demonstrates that CKD patients show effective response to Non-surgical periodontal therapy.