Plasma Myoglobin in the Early Diagnosis of Acute Myocardial Infarction

Plasma myoglobin appared to be more sensitive than creatine kinase-MB for the early diagnosis of acute myocardial infarction; using a cut-off value of 100 μ§/1, 90% of acute myocardial infarction cases were correctly recognized by plasma myoglobin 6 hours after the onset of ehest pain, with a diagnostic specificity of 100% for non-acute myocardial infarction ehest pain subjects. Plasma creatine kinase-MB showed a diagnostic sensitivity of 62% and a diagnostic specificity of 95% in the same group of patients.