Phosphoproteomic Analysis of Neonatal Regenerative Myocardium Revealed Important Roles of CHK1 via Activating mTORC1/P70S6K Pathway

Yi Fan,Yiwei Cheng,Yafei Li,Bing-Rui Chen,Zimu Wang,Tianwen Wei,Hao Zhang,Yueshuai Guo,Qi-Ming Wang,Yongyue Wei,Feng Chen,Jiahao Sha,Xuejiang Guo,Lian-Sheng Wang

Phosphoproteomic Analysis of Neonatal Regenerative Myocardium Revealed Important Roles of CHK1 via Activating mTORC1/P70S6K Pathway

2020

Yi Fan
Yiwei Cheng
Yafei Li
Bing-Rui Chen
Zimu Wang
Tianwen Wei
Hao Zhang
Yueshuai Guo
Qi-Ming Wang
Yongyue Wei
Feng Chen
Jiahao Sha
Xuejiang Guo
Lian-Sheng Wang

Background: In mammalian, regenerative therapy after myocardial infarction (MI) is hampered by the limited regenerative capacity of adult heart, while a transient regenerative capacity is maintaine...

Keywords:

Regenerative medicine
mTORC1
Internal medicine
Cardiology
Myocardial infarction
Medicine
Diabetes mellitus
P70S6 kinase
CHEK1
infant newborn
Kinase
Ribosomal protein s6
Cancer research

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