Small GTP-Binding Protein GDP Dissociation Stimulator Prevents Thoracic Aortic Aneurysm Formation and Rupture by Phenotypic Preservation of Aortic Smooth Muscle Cells

Masamichi Nogi,Kimio Satoh,Shinichiro Sunamura,Nobuhiro Kikuchi,Taijyu Satoh,Ryo Kurosawa,Junichi Omura,Md. Elias-Al-Mamun,Mohammad Abdul Hai Siddique,Kazuhiko Numano,Shun Kudo,Satoshi Miyata,Masatoshi Akiyama,Kiichiro Kumagai,Shunsuke Kawamoto,Yoshikatsu Saiki,Hiroaki Shimokawa

Small GTP-Binding Protein GDP Dissociation Stimulator Prevents Thoracic Aortic Aneurysm Formation and Rupture by Phenotypic Preservation of Aortic Smooth Muscle Cells

2018

Masamichi Nogi
Kimio Satoh
Shinichiro Sunamura
Nobuhiro Kikuchi
Taijyu Satoh
Ryo Kurosawa
Junichi Omura
Md. Elias-Al-Mamun
Mohammad Abdul Hai Siddique
Kazuhiko Numano
Shun Kudo
Satoshi Miyata
Masatoshi Akiyama
Kiichiro Kumagai
Shunsuke Kawamoto
Yoshikatsu Saiki
Hiroaki Shimokawa

Background: Thoracic aortic aneurysm (TAA) and dissection are fatal diseases that cause aortic rupture and sudden death. The small GTP-binding protein GDP dissociation stimulator (SmgGDS) is a cruc...

Keywords:

Aneurysm dissecting
Myocyte
Phenotype
Diabetes mellitus
Aortic rupture
Internal medicine
Cardiology
Thoracic aortic aneurysm
Dissection
Small GTP binding protein
Medicine
Abdominal aorta
Abdominal aortic aneurysm
Thoracic aorta
sudden death
Apolipoprotein E
Endocrinology
Angiotensin II

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