Abstract P146: Telomere Length, DNA Methylation, and Risk of Cardiovascular Diseases: Meta-EWAS of Four Multi-ethnic Prospective Cohorts

Pooja Subedi,Huaizhen Qin,Shelley A. Cole,Maria Tellez-Plaza,Arce Domingo-Relloso,Karin Haack,Danielle Fallin,Wan yee Tang,Simin Liu,Belinda L. Needham,Elisa T. Lee,Jason G. Umans,Barbara V. Howard,Yongmei Liu,Abraham Aviv,Daniel Levy,Ramachandran S. Vasan,Ana Navas-Acien,Jinying Zhao

Abstract P146: Telomere Length, DNA Methylation, and Risk of Cardiovascular Diseases: Meta-EWAS of Four Multi-ethnic Prospective Cohorts

2020

Pooja Subedi
Huaizhen Qin
Shelley A. Cole
Maria Tellez-Plaza
Arce Domingo-Relloso
Karin Haack
Danielle Fallin
Wan yee Tang
Simin Liu
Belinda L. Needham
Elisa T. Lee
Jason G. Umans
Barbara V. Howard
Yongmei Liu
Abraham Aviv
Daniel Levy
Ramachandran S. Vasan
Ana Navas-Acien
Jinying Zhao

Background: Biological aging assessed by both leukocyte telomere length (LTL) and DNA methylation (DNAm) has been associated with CVD and its risk factors. Moreover, LTL is epigenetically regulated...

Keywords:

Oncology
Medicine
Telomere
Ethnic group
Cardiology
Internal medicine
DNA methylation
Diabetes mellitus

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