Systemic lupus erythematosus.

: Systemic lupus erythematosus (SLE) is a complex multisystem autoimmune disease of unknown aetiology that is subject to period of exacerbation and remission. Treatments aimed at controlling disease activity remain primarily by immunosuppression, the prescribing of which is dependent on the development of any multisystem complications. With the establishment of dedicated lupus clinics using a multidisciplinary team approach, prognosis is better and treatment options continue to improve.