Abstract 4: Glucose Control and Risk of Tpa-Related Symptomatic Intracerebral Hemorrhage in Patients With Hyperglycemic Acute Ischemic Stroke: Preplanned Analysis From the SHINE Trial

Andrew M. Southerland,Nicole Chiota-McCollum,Mark R. Conaway,Ashley C. Bolte,Qi Pauls,Stephan A. Mayer,Creed Pettigrew,Thomas P. Bleck,Karen C. Johnston

Abstract 4: Glucose Control and Risk of Tpa-Related Symptomatic Intracerebral Hemorrhage in Patients With Hyperglycemic Acute Ischemic Stroke: Preplanned Analysis From the SHINE Trial

2021

Andrew M. Southerland
Nicole Chiota-McCollum
Mark R. Conaway
Ashley C. Bolte
Qi Pauls
Stephan A. Mayer
Creed Pettigrew
Thomas P. Bleck
Karen C. Johnston

Introduction: In acute ischemic stroke (AIS), hyperglycemia promotes enhanced blood brain barrier permeability, tissue acidosis, and oxygen free radicals, and may increase risk of post-tPA symptoma...

Keywords:

tissue acidosis
Internal medicine
Intracerebral hemorrhage
Medicine
Stroke
acute ischemic stroke
glucose control
Cardiology
in patient
blood brain barrier permeability

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