Abstract 24: Amyloidogenic V122I Transthyretin Variant is Associated With Progression of Adverse Cardiac Mechanics in Middle-aged African American Adults: The Coronary Artery Risk Development in Young Adults (CARDIA) Study

Arjun Sinha,Yinan Zheng,Yishu Qu,Drew Nannini,Lifang Hou,Sanjiv J. Shah,Clyde W. Yancy,Donald M. Lloyd-Jones,Laura Rasmuseen-Torvik,Sadiya S. Khan

Abstract 24: Amyloidogenic V122I Transthyretin Variant is Associated With Progression of Adverse Cardiac Mechanics in Middle-aged African American Adults: The Coronary Artery Risk Development in Young Adults (CARDIA) Study

2020

Arjun Sinha
Yinan Zheng
Yishu Qu
Drew Nannini
Lifang Hou
Sanjiv J. Shah
Clyde W. Yancy
Donald M. Lloyd-Jones
Laura Rasmuseen-Torvik
Sadiya S. Khan

Introduction: Direct-to-consumer testing (e.g. 23andme) reports now include common pathogenic variants in the transthyretin (TTR) gene, such as V122I. TTR cardiac amyloidosis due to V122I is an aut...

Keywords:

Young adult
Medicine
african american
Transthyretin
Internal medicine
Cardiology
cardiac mechanics
Diabetes mellitus
Artery

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