Efficacy of intraperitoneal catheter persistent ascites drainage in patients with hepatorenal syndrome

Objective To analyze the curative effect on the intraperitoneal catheter persistent drainage of ascites in patients with hepatorenal syndrome.Methods A total of 52 patients with hepatorenal syndrome were divided into 2 groups randomly. The Group A (n=28) was treated with the intraperitoneal catheter to drain the ascites persistently. The Group B (n=24) was treated with general medical therapy. Both groups received the basic treatment such as liver protection, infusion of albumin, restriction of sodium and water, the vasoactive substances, and so on. The clinical curative effect and the biochemical indicators for hepatic function, renal function, and electrolyte between the two groups after treatment were compared. The urine output, hospitalization days, and the costs were also compared.Results The urine volume, urea nitrogen, creatinine, and serum sodium in Group A were significantly improved after the treatment, whereas there was no significant changes in Group B. Group A had much better effect on increasing the urine volume than the control group (P0.01).The difference in albumin and ALT between the two groups was not statistically significant (P0.05). But the costs for hospitalization and amounts for albumin usage were higher in Group B (P0.05). Group A had better clinical curative effect than that of Group B.Conclusion Continuous ascites drainage has the advantages in treating patients with hepatorenal syndrome. It includes increasing the urine volume of the patients, reducing ascites and incidence of complications, and decreasing the hospitalization costs.