Role of Programmed Cell Death 4 (PDCD4)-Mediated Akt Signaling Pathway in Vascular Endothelial Cell Injury Caused by Lower-Extremity Ischemia-Reperfusion in Rats

Huanhuan Chen,Haifeng Zhu,Jin Yang,Yuefeng Zhu,Jinhua Mei,Haigang Shen,Kai Liang,Xiangyu Zhang

Role of Programmed Cell Death 4 (PDCD4)-Mediated Akt Signaling Pathway in Vascular Endothelial Cell Injury Caused by Lower-Extremity Ischemia-Reperfusion in Rats

2019

Huanhuan Chen
Haifeng Zhu
Jin Yang
Yuefeng Zhu
Jinhua Mei
Haigang Shen
Kai Liang
Xiangyu Zhang

Background We aimed to investigate the role of PDCD4-mediated Akt signaling pathway in vascular endothelial cell injury caused by ischemia-reperfusion in the lower extremities.

Keywords:

Internal medicine
Endocrinology
Medicine
Diabetes mellitus
Cancer research
Endothelial stem cell
Lower extremity ischemia
Akt/PKB signaling pathway
Programmed cell death
Von Willebrand factor
Thrombomodulin
Protein kinase B
Gene silencing
Enos
Superoxide dismutase

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