Abstract 31: Ultraearly Hematoma Growth: Multicenter External Validation of the Adjustment of Intracerebral Hemorrhage Volume by Onset-to-imaging Time

Background: The impact of baseline intracerebral hemorrhage (ICH) volume on hematoma growth (HG) and clinical outcome may vary widely depending on the onset-to-imaging time (OIT). We previously reported that the adjustment of initial ICH volume by OIT (coined as ultraearly HG, uHG) is a powerful tool for outcome prediction in acute ICH. We aimed to validate our previous findings in a multicenter external cohort and to assess the relationship between uHG and the CTA spot-sign. Methods: The PREDICT study was a prospective, observational cohort study of consecutive ICH patients 33% or >6 mL, early neurologic deterioration (END) as increase ≥4 points in the NIHSS score or death at 24 hours, and poor outcome as mRS score >2 at 3 months. Results: Two hundred and thirty-seven patients were included in this study. Med...