Study on the diagnosis and nursing value of diffusion weighted MR imaging based on neuroendocrine analysis in radiotherapy of laryngeal cancer

Abstract This paper uses 1.5T magnetic resonance to investigate the role of semi-quantitative parameters related to dynamic enhanced MRI (DCE-MRI) and the apparent diffusion coefficient (ADC) of diffusion-weighted imaging (DWI) in predicting and monitoring the efficacy of concurrent radiotherapy and chemotherapy for laryngeal cancer. The paper collected 58 newly diagnosed laryngeal cancer patients who were treated in our hospital from August 2016 to March 2018, 56 males and 2 females, with a median age of 57 years. The biopsy pathology was squamous cell carcinoma. The time signal curve (TIC) of tumour and related semi-quantitative parameters were measured before treatment, during treatment (radiotherapy dose 50Gy), at the end of treatment (nursing value after treatment). The study found that: TIC curve types and DCE-MRI-related semi-quantitative parameters can predict the efficacy of concurrent chemoradiotherapy for laryngeal cancer and hypopharyngeal cancer. Among the semi-quantitative parameters, SER56 has the greatest predictive value. The TICI type before treatment has a better prognosis than TICIII type The pre-ADC value is not enough to predict the efficacy; ADC value, DCE-MRI related semi-quantitative parameters and their change values before treatment have a certain effect on monitoring changes in water molecule diffusion movement and hemodynamic changes after tumour treatment, but Not enough to predict efficacy.