Apatinib for treating advanced intrahepatic cholangiocarcinoma after failed chemotherapy: A case report and literature review

AbstractRationale:Intrahepatic cholangiocarcinoma (ICC) originates from the secondary branch of the bile duct and the intrahepatic bile duct epithelial cells, and is a rare pathological type of primary liver cancer. Recently, apatinib has been successfully used for a variety of malignancies.Patient