Vaginal Glomus Tumor Presented as a Painless Cystic Mass

Abstract Objective. To present clinical and pathological findings of extremely rare vaginal glomus tumor. Methods. Clinical details were obtained from patient records. Histopathological examination included immunohistochemistry. Results. A 45-year-old menopausal woman had a 4-year history of painless cystic mass, 1.0 cm in diameter, on the anterior vaginal wall. Surgical excision of mass was uneventful. Histological examination revealed glomus tumor, primarily solid but also containing a clearly identifiable angiomatous component. Tumor cells showed prominent cytoplasmic immunostaining for vimentin and actin and negative staining for desmin, epithelial membrane antigen, pancytokeratin, Factor VIII, S-100, HMB-45, chromogranin, and estrogen, progesterone, and androgen receptors. Conclusion. Vaginal glomus tumor may be painless and, when the angiomatous component is evident, may appear as cystic mass.