LATE RENAL TRANSPLANT FAILURE DUE TO THE HEMOLYTIC-UREMIC SYNDROME

. A case is reported of hemolytic-uremic syndrome with irreversible renal failure in a young girl who had received a renal transplant 20 months previously. Splenectomy and high-dose steroid therapy were without effect on hemolysis and thrombocytopenia. Removal of the anuric kidney graft was followed by cessation of hemolysis and disappearance of thrombocytopenia. The microscopic lesions in the graft revealed microvascular disease, while histological signs of rejection were absent.