Higher serum alkaline phosphatase activity in infants born to vitamin D–deficient mothers

Summary Our research shows that the newborns of vitamin D–deficient mothers have higher serum alkaline phosphatase (ALP) activity compared with those of vitamin D–non-deficient mothers, which is likely related to increased bone turnover rather than just being a marker for bone formation. This has a potential negative impact on fetal bone development and subsequent skeletal growth.