Inhibition of hepatitis C virus replication by chloroquine targeting virus-associated autophagy.
2010
Background
Autophagy has been reported to play a pivotal role on the replication of various RNA viruses. In this study, we investigated the role of autophagy on hepatitis C virus (HCV) RNA replication and demonstrated anti-HCV effects of an autophagic proteolysis inhibitor, chloroquine.
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