TARGT Gene Therapy Platform for Correction of Anemia in End-Stage Renal Disease

Shany Blum,Nir Shapir,Reem Miari,Benny Lerner,Belly Koren,Keren Doenyas-Barak,Shai Efrati,Pablo E. Pergola,Doron Schwartz,Gil Chernin,Yoram Yagil,Serge Guzy,Abraham Nyska,Garry A. Neil

TARGT Gene Therapy Platform for Correction of Anemia in End-Stage Renal Disease

2017

Shany Blum
Nir Shapir
Reem Miari
Benny Lerner
Belly Koren
Keren Doenyas-Barak
Shai Efrati
Pablo E. Pergola
Doron Schwartz
Gil Chernin
Yoram Yagil
Serge Guzy
Abraham Nyska
Garry A. Neil

A new protein-delivery platform can provide sustained secretion of recombinant human erythropoietin with the use of small, transduced autologous dermal implants. Study patients with end-stage renal disease were found to have maintenance of stable hemoglobin levels.

Keywords:

Erythropoietin
Disease
Hemoglobin
Anemia
Surgery
Diabetes mellitus
Medicine
Genetic enhancement
Recombinant DNA
Secretion
end stage renal disease

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