Refractory macular edema in X-linked juvenile retinoschisis

X-linked juvenile retinoschisis (XLRS) is one of the most common X-linked inherited, bilateral vitreoretinal dystrophies affecting males in the first two decades of life. In this article, we present a case report of a young man who presented with gradual decrease in visual acuity in both eyes that was attributed to macular edema and foveal schisis in the inner retinal layers. He was investigated by appropriate ocular images which were consistent with a diagnosis of XLRS. He was treated by anti-vascular endothelial growth factor (anti-VEGF) intravitreal injection, dorzolamide eye drops and intravitreal steroids injection without improvement.