Tu1201 Effects of Transcutaneous Electrical Acupuncuture on Vagal Function and CNS Control for Nausea in Patients With Diabetic Gastroparesis

The introduction of high resolution esophageal motility (HREM) has redefined the understanding of esophageal motor disorders (EMD) as new patterns have been identified. The prevalence of these disorders using HREM has not been studied in specific populations. AIM: Describe the prevalence of EMD in a Mexican population. METHDOS: A prospective study was conducted in four community referral hospitals (750 beds) of the metropolitan area of the northern Mexican city of Monterrey (third largest city in the country, population > 4 million). All consecutive patients referred for esophageal motility testing (EMT) during March 1st 2013 to August 31, 2014 were included. Data collected included demographics and indications. EMT was performed with Given ManoScanTM HREM and the Chicago Classification was employed for diagnostic criteria. All studies were interpreted by a single experienced gastroenterologist with focused interest on esophageal diseases. RESULTS: During the study period, 342 patients had EMT. Six were excluded due to inability to tolerate the test. A normal EMT was found in 214 (64%). The most frequent motor disorder recognized was frequent failed peristalsis (n = 35, 29%), followed by weak peristalsis with small breaks (n = 26, 21%). Table 1 summarizes our manometric findings grouped based on the test indication. CONCLUSIONS: This is the first descriptive study of a large Mexican population undergoing EMT using HREM. In this population, the majority of these patients were studied for GERD. Most patients (64%) had a normal test. For those with abnormal results, a spectrum of abnormalities was observed with peristaltic defects representing the most common abnormality. Further studies are required to compare the scope of our findings with USA and other world-wide populations. Table 1. Manometric findings