Assessing quality of life using WHOQOL-BREF: A cross-sectional insight among patients on warfarin in Malaysia

Abstract Background and aim The effect of anticoagulation control on overall Health-Related Quality of Life (HRQoL) in patients taking warfarin in Malaysia has not been explored yet. Therefore, this study aimed to evaluate HRQoL among patients on warfarin in Malaysia. Methods HRQoL among patients on warfarin was measured using WHOQOL-BREF (World Health Organization Quality of life Assessment: Brief Version). Descriptive and inferential statistical analysis was done using Statistical Package for the Social Sciences (SPSS) version 22. Results: Out of 319 patients, more female patients were observed than the males (n=221, 69.3%, and n=98, 30.7% respectively). Mean scores for the physical (61.14±15.96), psychological (68.58±16.11), social (63.55±27.06) and environmental domains (62.78±17.58) were observed. Statistically, a significant association was found between the comorbidities other than CVDs with health satisfaction (p=0.002), physical (p=0.001), psychological (p Conclusion Patients had overall better perceived HRQoL scores in the psychological domain as compared with the rest of the domains of the WHOQOL-BREF. Age, gender, employment status, education level, the indication of use and duration of warfarin therapy associated with overall perceived HRQoL.