Prognostic value of hepatic encephalopathy for survival of patients with liver failure: A systematic review and meta-analysis

Abstract Introduction and aim The aim of this paper was to evaluate the association of hepatic encephalopathy with survival of patients with liver failure. Materials and methods We retrieved the relevant articles from the PubMed, Embase and Cochrane Library, up to May 2017. The pooled odds ratio (OR) as well as their 95% confidence intervals (CI) was calculated by the software of R package version 3.12. Results Total 13 studies with 2071 liver failure patients were included and reanalyzed in this meta-analysis. The results proved the prognostic value of hepatic encephalopathy for survival of patients with liver failure (OR = 5.62, 95%CI = 6.30–9.82, P Conclusions The results proved that hepatic encephalopathy was a prognostic factor of survival in patients with liver failure.