Sustained Klotho delivery reduces serum phosphate in a model of diabetic nephropathy

Julia M. Hum,Linda Maureen OBryan,Arun K. Tatiparthi,Erica L. Clinkenbeard,Pu Ni,Martin S. Cramer,Manoj Bhaskaran,Robert L. Johnson,Jonathan M. Wilson,Rosamund C. Smith,Kenneth E. White

Sustained Klotho delivery reduces serum phosphate in a model of diabetic nephropathy

2019

Julia M. Hum
Linda Maureen OBryan
Arun K. Tatiparthi
Erica L. Clinkenbeard
Pu Ni
Martin S. Cramer
Manoj Bhaskaran
Robert L. Johnson
Jonathan M. Wilson
Rosamund C. Smith
Kenneth E. White

In this work, systemic and continuous delivery of the “soluble” or “cleaved” form of the FGF23 coreceptor α-Klotho (cKL) via adeno-associated virus to a rodent model of diabetic nephropathy (DN), t...

Keywords:

Diabetes mellitus
Serum phosphate
Anesthesia
Endocrinology
Diabetic nephropathy
Virus
Chemistry
Phosphate
Klotho
Internal medicine
rodent model

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