Relation between Hemoglobin and HbA1c in Non-GDM Mothers.

2014 
Hemoglobin A1c (HbA1c) is the major form of Glycohemoglobin. It correlates with Glycemic control and is elevated abnormally in chronic hyperglycemic diabetic patients. Prior studies state that pregnancy significantly alters the HbA1c levels and the erythrocyte turnover (anemia) also affects HbA1c levels. This study was designed to assess the relationship between the HbA1c concentration and the Hemoglobin levels among non-diabetic pregnant mothers. This is a descriptive cross sectional study. A total of 50 non diabetic pregnant mothers were selected and divided into two groups based on the Hemoglobin levels. Group A with Hemoglobin less than 10gms% and Group B with Hemoglobin more than 10gms%. The Hemoglobin level in both the groups was compared with their HbA1c levels along with the Fasting and Postprandial blood sugar, BMI and Age. This study showed significantly raised HbA1c levels among anemic group (5.6±0.43) when compared to normal group(5.1±0.46) with Pearson’s correlation r = -0.5 (P=0.000). Our study shows that in Non-GDM mothers with anemia, have an increased HbA1c levels and that precautions should be taken while interpreting the Glycemic status and control based on HbA1c levels.
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