Abstract 18230: Very Low Rates of LDL Goal Attainment in Real Clinical Setting: Interim Results of a Nation-wide Registry of Familial Hypercholesterolemia in Turkey (A-HIT 2)

Introduction: Familial hypercholesterolemia (FH) is a common genetic disease of high levels of cholesterol leading to premature atherosclerosis. Attainment of LDL-goals with lipid-lowering is the mainstay of treatment for prevention of premature cardiovascular events. Study was conducted to provide insight to the clinical status of FH pts in real clinical setting. Hypothesis: FH patients are undertreated even in specialized centers. Methods: A-HIT2 is a registry of adult FH pts admitting to outpatient clinics. Pts were recruited from 30 outpatient clinics representing 12 Nuts statistical Regions in Turkey. Primary objective of this cross-sectional study, was to detect the clinical status and management of pts diagnosed with FH in Turkey. Patients with a total score of > 2 according to DLCN criteria were accepted as possible FH. Results: 684 FH pts (mean age: 54±10 years, 57% women) were enrolled from sites specialized on cardiology, internal medicine, and endocrinology. Mean DLCN score was: 6.37±4.09. At ...