Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

Bakhtawar K. Mahmoodi,Vinicius Tragante,Marcus E. Kleber,Michael V. Holmes,Amand F. Schmidt,Raymond O. McCubrey,Laurence J. Howe,Kenan Direk,Hooman Allayee,Ekaterina V Baranova,Peter S. Braund,Graciela Delgado,Niclas Eriksson,Crystel M. Gijsberts,Yan Gong,Jaana Hartiala,Mahyar Heydarpour,Gerard Pasterkamp,Salma Kotti,Pekka Kuukasjärvi,Petra A. Lenzini,Daniel Levin,Leo-Pekka Lyytikäinen,Jochen D. Muehlschlegel,Christopher P. Nelson,Kjell Nikus,Anna P. Pilbrow,W.H. Wilson Tang,Sander W. van der Laan,Jessica van Setten,Ragnar O. Vilmundarson,John E. Deanfield,Panos Deloukas,Frank Dudbridge,Stefan James,Ify Mordi,Andrej Teren,Thomas O. Bergmeijer,Simon C. Body,Michiel L. Bots,Ralph Burkhardt,Rhonda M. Cooper-DeHoff,Sharon Cresci,Nicolas Danchin,Robert N. Doughty,Diederick E. Grobbee,Emil Hagström,Stanley L. Hazen,Claes Held,Imo E. Hoefer,G. Kees Hovingh,Julie A. Johnson,Marcin P. Kaczor,Mika Kähönen,Olaf H. Klungel,Jari Laurikka,Terho Lehtimäki,Anke H. Maitland-van der Zee,Ruth McPherson,Colin N. A. Palmer,Adriaan O. Kraaijeveld,Carl J. Pepine,Marek Sanak,Naveed Sattar,Markus Scholz,Tabassome Simon,John A. Spertus,Alexandre F.R. Stewart,Wojciech Szczeklik,Joachim Thiery,Frank L.J. Visseren,Johannes Waltenberger,A. Mark Richards,Chim C. Lang,Vicky A. Cameron,Axel Åkerblom,Guillaume Paré,Winfried März,Nilesh J. Samani,Aroon D. Hingorani,Jurriën M. ten Berg,Lars Wallentin,Folkert W. Asselbergs,Riyaz S. Patel

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

2020

Bakhtawar K. Mahmoodi
Vinicius Tragante
Marcus E. Kleber
Michael V. Holmes
Amand F. Schmidt
Raymond O. McCubrey
Laurence J. Howe
Kenan Direk
Hooman Allayee
Ekaterina V Baranova
Peter S. Braund
Graciela Delgado
Niclas Eriksson
Crystel M. Gijsberts
Yan Gong
Jaana Hartiala
Mahyar Heydarpour
Gerard Pasterkamp
Salma Kotti
Pekka Kuukasjärvi
Petra A. Lenzini
Daniel Levin
Leo-Pekka Lyytikäinen
Jochen D. Muehlschlegel
Christopher P. Nelson
Kjell Nikus
Anna P. Pilbrow
W.H. Wilson Tang
Sander W. van der Laan
Jessica van Setten
Ragnar O. Vilmundarson
John E. Deanfield
Panos Deloukas
Frank Dudbridge
Stefan James
Ify Mordi
Andrej Teren
Thomas O. Bergmeijer
Simon C. Body
Michiel L. Bots
Ralph Burkhardt
Rhonda M. Cooper-DeHoff
Sharon Cresci
Nicolas Danchin
Robert N. Doughty
Diederick E. Grobbee
Emil Hagström
Stanley L. Hazen
Claes Held
Imo E. Hoefer
G. Kees Hovingh
Julie A. Johnson
Marcin P. Kaczor
Mika Kähönen
Olaf H. Klungel
Jari Laurikka
Terho Lehtimäki
Anke H. Maitland-van der Zee
Ruth McPherson
Colin N. A. Palmer
Adriaan O. Kraaijeveld
Carl J. Pepine
Marek Sanak
Naveed Sattar
Markus Scholz
Tabassome Simon
John A. Spertus
Alexandre F.R. Stewart
Wojciech Szczeklik
Joachim Thiery
Frank L.J. Visseren
Johannes Waltenberger
A. Mark Richards
Chim C. Lang
Vicky A. Cameron
Axel Åkerblom
Guillaume Paré
Winfried März
Nilesh J. Samani
Aroon D. Hingorani
Jurriën M. ten Berg
Lars Wallentin
Folkert W. Asselbergs
Riyaz S. Patel

Background: Studies examining the role of factor V Leiden among patients at higher risk of atherothrombotic events, such as those with established coronary heart disease (CHD) are lacking. Given th...

Keywords:

Medicine
coronary heart disease
Recurrent myocardial infarction
Diabetes mellitus
Factor V Leiden
Cardiology
Genius
Internal medicine
secondary prevention
Coronary artery disease
Individual participant data

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