Monogenic Stroke Diseases
2021
Stroke is in most cases the consequence of a multifactorial predisposition. However, a number of rare monogenic diseases leading to stroke have been reported and several genes have been identified whose mutations lead to monogenic cerebral small vessel diseases (CSVD), inherited cerebral vascular malformations, and dysplasia. This review focuses on monogenic cerebral small vessel diseases and the recent genetic data obtained in this field which can be useful for precision medicine.
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