Gastroesophageal Reflux Diseases and Lifestyle Factors

Gastroesophageal reflux disease (GERD) is the most common upper gastrointestinal disorder and has been increasing in the past two decades in Japan. Several studies showed significant associations between GERD and lifestyle factors. In this chapter, we focused on obesity, metabolic syndrome, diabetes, hypertension, dyslipidemia, cigarette smoking, alcohol drinking, and late meals. We also discussed how these factors affect pathogenesis of GERD. We recommend modification of lifestyle factors associated with GERD as a basic therapeutic strategy.