Gray-scale second harmonic imaging of the liver with galactose-based microbubbles

RATIONALE AND OBJECTIVESThe authors evaluate the efficacy of SHU 508A, a galactose-based contrast agent used in gray-scale second harmonic imaging in vitro and in vivo experiments.METHODSA Toshiba prototype harmonic imaging system(2.5/5.0 MHz) was used with SHU 508A in a phantom experiment and to im