Duodenogastric reflux eradicates Helicobacter pylori after distal gastrectomy.

Background/Aims: Patients who undergo distal gastrectomy often develop duodenogastric reflux and preoperative H. pylori infection is eradicated spontaneously after distal gastrectomy in some patients. However, whether a causal relationship exists has not yet been studied. This report examines the correlation between H. pylori eradication and the amount of duodenogastric reflux following distal gastrectomy. Methodology: Among 72 consecutive patients who underwent curative distal gastrectomy with radical lymphadenectomy for gastric cancer, 37 patients lead H. pylori infection preoperatively and were included in this study. The period of bile reflux (percent time) into the gastric remnant was measured with the Bilitec 2000 under standardized conditions on the 14th day after the surgery. Endoscopic examination was performed to determine the presence of H. pylori infection on week 12 after surgery. Results: The percent time was higher in patients whose H. pylori infection had been eradicated after distal gastrectomy (58.1 ±9.2%) than in patients who had H. pylori infection after distal gastrectomy (33.8±5.7%). Conclusions: Duodenogastric reflux correlates with spontaneous eradication of H. pylori infection following distal gastrectomy.