Short communication Mechanisms of arachidonic acid induced glial swelling

Accumulation of arachidonic acid AA in the brain during ischaemia may contribute to development of brain oedema. In this study we investigated the effect of selected drugs on AA-induced cytotoxic brain oedema in C6 glioma cells. Suspended C6 glioma cells were . preincubated with drugs and AA 0.1 mM was added. When no drug was administered cell volume increased immediately after the .