Quality of life and its influencing factors among severe aortic stenosis patients after transcatheter aortic valve replacement

Objective To investigate the quality of life in patients with severe aortic stenosis (AS) after transcatheter aortic valve replacement (TAVR) and analyze the related influencing factors. Methods A total of 139 patients who had undergone TAVR in Department of Cardiovascular Medicine, West China Hospital, Sichuan University, were selected through the hospital electronic medical record system from April of 2012 to April of 2017. By using the General Information Questionnaire for Patients, Charlson's co-morbidity Index (CCI) , Morisky Medication Adherence Scale, and China Cardiovascular Quality of Life Questionnaire (CQQC) , their life quality were investigated and the influencing factors were analyzed. Results The average score of CQQC after TAVR was (78.76±16.52) , lower than the national norm. There were statistical difference in the scores of CQQC in patients with different ages, marital status, educational background, cardiac function preoperation, CCI weight, smoking status, drinking status, and regular exercise status (P<0.05) . Stepwise regression analysis indicated that, age, marital status, cardiac function preoperation, time of length postoperation and regular exercise could be included into the regression modal, accounting for 34.9% of variances. Conclusions The quality of life of patients after TAVR is low. Age, marital status, preoperative cardiac function, postoperative time and regular exercise will affect the quality of life of patients. It is suggested that medical staff should pay attention to the quality of life of TAVR patients after operation and carry out targeted nursing intervention and health education actively, as well as scientific rehabilitation exercise so as to improve the quality of life of TAVR patients after operation. Key words: Aortic stenosis; Transcatheter aortic valve replacement; Quality of life; Influencing factors