Etude de la cristallurie lors du traitement prophylactique de la lithiase urinaire par l'allopurinol, l'hydrochlorothiazide, l'oxyde de manganèse, les diphosphonates et l'acide propionohydroxamique

: The study of cristalluria was used as a method to evaluate the severity of nephrolithiasis and the efficacy of different drug therapies. The number and dimensions of urinary crystals as well as the number of crystal aggregates, were determined in patients with infected calcium or uric acid nephrolithiasis. Crystalluria was studied before therapy and at 6 and 12 months during treatment. Marked reduction of crystalluria in patients with uric acid stones treated with allopurinol and in patients with infected stones treated with antibiotics and propionohydroxamic acid (PHA) was observed. Reduction of crystalluria in the group of patients treated with antibiotics alone was lower. We stress usefulness of the study of crystalluria in stone formers, which is also relatively easy to carry out.