Improved anticancer delivery of paclitaxel by albumin surface modification of PLGA nanoparticles.

Mehdi Esfandyari-Manesh,Seyed Hossein Mostafavi,Reza Faridi Majidi,Mona Noori Koopaei,Nazanin Shabani Ravari,Mohsen Amini,Behrad Darvishi,Seyed Nasser Ostad,Fatemeh Atyabi,Rassoul Dinarvand

Improved anticancer delivery of paclitaxel by albumin surface modification of PLGA nanoparticles.

2015

Mehdi Esfandyari-Manesh
Seyed Hossein Mostafavi
Reza Faridi Majidi
Mona Noori Koopaei
Nazanin Shabani Ravari
Mohsen Amini
Behrad Darvishi
Seyed Nasser Ostad
Fatemeh Atyabi
Rassoul Dinarvand

Background Nanoparticles (NPs) play an important role in anticancer delivery systems. Surface modified NPs with hydrophilic polymers such as human serum albumin (HSA) have long half-life in the blood circulation system.

Keywords:

Biophysics
Drug delivery
Nanoparticle
PLGA
Pharmacology
Albumin
Paclitaxel
Surface modification
Human serum albumin
Medicine
Serum albumin
Chromatography

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