Mast Cells Regulate Wound Healing in Diabetes

Diabetic foot ulceration is a severe complication of diabetes (DM) that lacks effective treatment. Mast cells (MCs) contribute to wound healing, but their role in DM skin is poorly understood. Here we show that the number of degranulated MCs is increased in unwounded forearm and foot skin of DM patients, and unwounded dorsal skin of DM mice (p