Testosterone supplementation in the patient with erectile dysfunction

Erectile dysfunction and hypogonadism are becoming two of the most frequently diagnosed sexual dysfunctions in men. They are often diagnosed together, and more men than before are being treated with both testosterone and phosphodiesterase type 5 inhibitors. Testosterone supplementation is a safe and effective treatment for men with hypogonadism, especially if they have erectile dysfunction as a result of hypogonadism. Testosterone supplementation for men with hypogonadism should be reserved for those with low serum testosterone accompanying the symptoms of hypogonadism, including erectile dysfunction. A careful baseline monitoring of prostate-specific antigen (PSA), a complete blood count, and an initial serum testosterone level are essential for initiation of testosterone supplementation. Clinicians must carefully monitor treatment, including both PSA monitoring and a complete blood count at regular intervals.