Down regulation of type 3 deiodinase in the hypothalamus during inflammation

Emmely M. de Vries,Olga V. Surovtseva,Winnie G. Vos,Roni F. Kunst,Mieke van Beeren,Joan Kwakkel,Olivier Chassande,Mariëtte T. Ackermans,Eric Fliers,Anita Boelen

Down regulation of type 3 deiodinase in the hypothalamus during inflammation

2019

Emmely M. de Vries
Olga V. Surovtseva
Winnie G. Vos
Roni F. Kunst
Mieke van Beeren
Joan Kwakkel
Olivier Chassande
Mariëtte T. Ackermans
Eric Fliers
Anita Boelen

Background: Inflammation is associated with marked changes in cellular thyroid hormone (TH) metabolism in triiodothyronine (T3) target organs. In the hypothalamus, type 2 deiodinase (D2), the main ...

Keywords:

Internal medicine
Deiodinase
Endocrinology
Inflammation
Diabetes mellitus
Hypothalamus
Medicine
Downregulation and upregulation
Triiodothyronine
NF-κB
Thyroid
Hormone

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