RIFLE Criteria in Critically Ill Neonates with Acute Kidney Injury

Introduction: Diagnosis of neonatal acute kidney injury (AKI) is a difficult dilemma and there is no consensus in this regard . Based on RIFLE criteria the definition of ARF is changed lately in adult and pediatric groups. Studies to evaluate the RIFLE criteria in the definition of neonatal ARF have not been performed. The aim of this study was to determine prevalence of AKI based on old definition of ARF and RIFLE criteria separately. Materials and Methods : This descriptive study was conducted on 904 critically ill neonates. The authors determined the RIFLE criteria for each neonate based on serum creatinine and urine output at the second day of admission. The RIFLE acronym stands for risk, injury, failure, loss of kidney function and end stage renal disease . Prevalence of AKI was determined based on old definition of ARF and RIFLE criteria separately . Results: Based on RIFLE criteria, 22.5% of study group had normal renal function and 77.5% had AKI at the second day of admission. Among patients with AKI 43% met the risk, 51% the injury and about 6% the failure criterion. Based on old definition of ARF in neonates, the prevalence of ARF in our study group was 3.2%. There was a significant difference between AKI prevalence by RIFLE criteria and the former definition (P<0.001). Conclusions: The RIFLE criterion is a simple tool for the detection and classification of AKI in NICUs. Keywords : Acute Kidney Injury; Newborn Intensive Care Units; Critically Ill. Normal 0 false false false EN-US X-NONE AR-SA /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;}