Clinical Reasoning: Worsening neurologic symptoms in a brain tumor patient

A 65-year-old woman diagnosed with a right parietal-occipital glioblastoma after presenting with hemianopia was treated with 2 surgical resections including carmustine wafer placement, radiotherapy with concurrent chemotherapy with temozolomide, and adjuvant chemotherapy with temozolomide and bevacizumab, an anti-angiogenic agent targeting vascular endothelial growth factor (VEGF).