Atypical pyogenic granuloma of gingiva with exuberant proliferation of myofibroblasts – A case report

Abstract Oral pyogenic granulomas are relatively common benign mucocutaneous lesions commonly associated to local irritation or trauma. These are typically solitary and vascular. The condition is often associated with pain and sometimes with masticatory and esthetic difficulties. Since the atypical oral pyogenic granuloma is indistinguishable histopathologically from other lesions so immunohistochemical examination is required for final diagnosis. The authors present a case report of a large size (4 × 4 cm) atypical pyogenic granuloma that mimics malignant tumor in a 40-year-old man in the posterior maxilla, diagnosed through clinical, histopathological and immunohistochemical examination. Oral pyogenic granulomas are well documented in literature. However their occurrence in oral cavity can present with unusual clinical and histological features that appear as malignancies. Careful diagnosis of this benign tumor is important to avoid unnecessary aggressive therapy.