Phase II trial of valproic acid combined with cisplatin-based chemoradiation in locally advanced (LA) head and neck squamous cell carcinoma (HNSCC) patients (pts).

Milena Perez Mak,Fátima Solange Pasini,Lixia Diao,Fabyane Oliveira Teixeira Garcia,Tiago Kenji Takahashi,Alex Vitorio Amadio,Sheila Aparecida Coelho Siqueira,Laura Sichero,Igor Snitcovsky,Marco Aurélio Vamondes Kulcsar,Jing Wang,Gilberto de Castro

Phase II trial of valproic acid combined with cisplatin-based chemoradiation in locally advanced (LA) head and neck squamous cell carcinoma (HNSCC) patients (pts).

2017

Milena Perez Mak
Fátima Solange Pasini
Lixia Diao
Fabyane Oliveira Teixeira Garcia
Tiago Kenji Takahashi
Alex Vitorio Amadio
Sheila Aparecida Coelho Siqueira
Laura Sichero
Igor Snitcovsky
Marco Aurélio Vamondes Kulcsar
Jing Wang
Gilberto de Castro

e17546Background: Cisplatin-based chemoradiation (CRT) offers LA HNSCC pts a high local control rate, however, relapses are frequent. Here we evaluated if epigenetic regulation by VA, a histone dea...

Keywords:

Cisplatin
Pathology
Head and neck squamous-cell carcinoma
Valproic Acid
Cancer research
Medicine
Epigenetics
Oncology
Internal medicine
locally advanced
control rate
Histone

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