Konjenital diafragma hernisinde yaşam prediktörleri: 10 yıllık deneyimin multivariate analizi

The purpose of this study was to establish a method by which independent predictors of survival could be determined and used to select CDHpatients who may benefit from rescue therapy. Data from our 10-year, single institutional experience of 62 infants with CDH were analyzed. Fifteen preoperative and seven intraoperative variables were analyzed. Stepwise logistic regression analysis yielded a prediction equation with four independent, statistically significant (Pl0.05) predictors of survival: lower VI, higher BW, higher 5-minute APGAR, and lower PaCO2. Using a survival probability of l20%, this equation yielded a sensitivity of 94% and specificity of 82% in selecting those patients with CDH who failed conventional management. We conclude that the preoperative values for VI, BW, 5-minute APGAR, and PaCO2 of neonates with CDH in our institution can be used to select those patients with predicted high mortality who may benefit from salvage therapy. [Journal of Turgut Ozal Medical Center 1997;4(2):225-229] Key words: Hernia, diaphragmatic, congenital, outcome, newborn, pediatrics