Enterectomy During Pregnancy for Mesenteric Vein Thrombosis Factor V Leiden Homozygosity

Abstract Background: Pregnant women carrying the factor V Leiden (FVL) mutation have a higher risk of venous thromboembolism. Case: A 39-year-old woman, homozygous for factor V Leiden mutation, presented with abdominal pain in the 33rd week of pregnancy. The patient suffered from mesenteric vein thrombosis. Results: Immediate cesarean birth was followed by a partial enterectomy. Conclusions: When signs of peritonitis are present, as in this case, successful treatment of mesenteric vein thrombosis mandates early resection of the infarcted bowel and mesentery to encompass the entire thrombotic process. In the presence of thrombophilia, the patient should also be given antepartum and postpartum low–molecular-weight heparin prophylaxis. (J GYNECOL SURG 27:111)