A multicentre randomised trial of amniotomy in spontaneous first labour at term

Objective To measure the effect of a policy of routine amniotomy on nulliparous labour. Design A multicentre randomised controlled trial. Subjects One thousand four hundred and sixty-three nulliparous women in spontaneous labour at term with intact membranes and a single cephalic fetus. Interventions To have the membranes ruptured routinely early in labour or left intact for as long as possible. Main outcome measures Duration of labour, operative and instrumental delivery rates, use of analgesia, perinatal death, neonatal convulsions and admission to special care. Results Median duration of labour was 8-4 h in the early rupture group and 9-4 h in the late group