Impact of HbAlc on acute cardiac states.

2011 
Results:- Out of the 166 patients, 92 were diabetic (group A) and 74 were non diabetic (group B). The mean HbA1c of group A was 8.4 + 1.9% and that of group B was 5.7 + 0.6%. Risk factors like dyslipidemia, hypertension, previous history of heart disease and triple vessel disease were found more in group A than in group B. History of smoking, positive family history of heart disease, and angina as a presenting symptom were more in group B. Complications like heart failure and post infarction angina occurred significantly more in patients with diabetes. In group A, unstable angina, ST elevation myocardial infarction, cardiac failure, accelerated hypertension, dilated cardiomyopathy and triple vessel disease were seen in a significantly higher proportion of patients with poor glycemic control (HbA1c ≥ 7%) compared to patients with HbA1c level < 7%. In group B, 72/74 (97.2%) patients had HbA1c levels ≥ 5%, 68.8% of whom had HbA1c levels of ≥ 5.6%. Conclusion:-Severity and complications of heart disease were significantly higher in diabetics and showed a significant correlation with HbA1c. A large number of non diabetics presenting with acute cardiac states i.e. 97.2%, had HbA1c values ≥ 5%.
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