Application of Synthetic Sinogram Based Low-Dose CT Simulation and Fold-Preserving Electronic Cleansing Technique for CT Colonography

This study evaluates the performance of the electronic cleansing technique in ultra-low-dose CT colonography, and explores the potential limit of the dose level which hampers the proper working of the electronic cleansing. We applied a synthetic sinogram-based low-dose CT simulation technique to the DICOM images CT colonography studies to generate a set of ultra-low-dose CT colonography dataset ranging 20, 10, 5, and 1 mAs conditions. A fold-preserving electronic cleansing technique was applied to those ultra-low-dose CT colonography CTC dataset and the tagging cleansing performance was evaluated for each dose-level.