Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma

Marrah E. Lachowicz-Scroggins,Eleanor M. Dunican,Annabelle R. Charbit,Wilfred W. Raymond,Mark R. Looney,Michael C. Peters,Erin D. Gordon,Prescott G. Woodruff,Emma Lefrançais,Brenda R. Phillips,David T. Mauger,Suzy Comhair,Serpil C. Erzurum,Mats W. Johansson,Nizar N. Jarjour,Andrea M. Coverstone,Mario Castro,Annette T. Hastie,Eugene R. Bleecker,Merritt L. Fajt,Sally E. Wenzel,Elliot Israel,Bruce D. Levy,John V. Fahy

Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma

2019

Rationale: Extracellular DNA (eDNA) and neutrophil extracellular traps (NETs) are implicated in multiple inflammatory diseases. NETs mediate inflammasome activation and IL-1β secretion from monocyt...

Keywords:

Anesthesia
Caspase 1
Microbiology
Caspase
Extracellular
Myeloperoxidase
DNA
Inflammasome
Secretion
Medicine
Neutrophil extracellular traps
Asthma
Diabetes mellitus
Immunology
extracellular dna
severe asthma

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